🗞 Medical Articles
Topic: Lithium for Bipolar Disorder and Risk of Thyroid Dysfunction and Chronic Kidney Disease
Study: Retrospective cohort (2002–2018, Hong Kong), patients ≥15 years with new bipolar diagnosis
Results:
▪️Increased risk of hypothyroidism (aHR 2.00) and CKD stage ≥3 (aHR 1.35) vs. non-lithium treatments
▪️Higher lithium levels linked to greater risks of thyroid and kidney issues
▪️Identified risk thresholds: >0.50 mEq/L for thyroid disorders, >0.58 mEq/L for CKD
Clinical Impact: Guides optimal lithium dosing to balance efficacy and safety, supporting personalized bipolar treatment.
Link: https://pubmed.ncbi.nlm.nih.gov/39932712/
@HakimApps_Guideline
Source: PubMed
Topic: Lithium for Bipolar Disorder and Risk of Thyroid Dysfunction and Chronic Kidney Disease
Study: Retrospective cohort (2002–2018, Hong Kong), patients ≥15 years with new bipolar diagnosis
Results:
▪️Increased risk of hypothyroidism (aHR 2.00) and CKD stage ≥3 (aHR 1.35) vs. non-lithium treatments
▪️Higher lithium levels linked to greater risks of thyroid and kidney issues
▪️Identified risk thresholds: >0.50 mEq/L for thyroid disorders, >0.58 mEq/L for CKD
Clinical Impact: Guides optimal lithium dosing to balance efficacy and safety, supporting personalized bipolar treatment.
Link: https://pubmed.ncbi.nlm.nih.gov/39932712/
@HakimApps_Guideline